Nitric Oxide (NO ) & Erectile Dysfunction Shockwave PRP Botox Trimix Boca Raton Men's Medspa

Boosting Nitric Oxide (NO) and Erectile Dysfunction, Heart Disease & Stroke

Nitic Oxide (NO) and The Arousal State

Although most men don’t want to talk about it, the majority of men will experience Erectile Dysfunction (ED) in their lifetime. The role of Nitric Oxide (NO) When men get aroused, the blood vessels in the penis relax and which allows the penis to fill with blood and become erect.   When one is 18 the wind blows and things happen. But, as men age things slow down, morning erections become less frequent, and eventually one can no longer perform under the sheets.    Therefore, Men accepted this slow down as a normal part of again. But in 1998 the little blue pill, Viagra, gave men their life back.  Unfortunately, this Euphoria was short lived, and eventually, despite increasing the dose, the pills stopped working.

Nitric Oxide (NO) and the Nobel Prize

Also, in 1998 Nobel Laureates discovered the key role of Nitric Oxide (NO) in cardiovascular health and vasodilation. NO diffuses across the smooth muscles lining blood vessels and activates cyclic guanosine monophosphate (cGMP).  As a result, blood vessels relax and dilate lowering risk of heart disease, stroke and improving erectile dysfunction.

Decrease of Nitric (NO) with Age

As we age, our levels of Nitric Oxide decreases resulting in a cascade of events contributing to cardiovascular disease and erectile dysfunction.  Viagra, a Phosphodiesterase type 5 (PDE5) inhibitor works by blocking the effects of PDE5 enzyme in our blood vessels which breaks down the blood vessel relaxing agent,  cGMP. 

The Anatomy of an Erection and Nitric Oxide (NO)

1. Vasodilation:  In the penis, the blood vessels are in a constant “contracted” state. In order for an erection to occur, the blood vessels must relax.

2. Role of Nitric Oxide (NO):  When sexually aroused,  NO activates cGMP.  As the smooth muscles in the blood vessels walls relax, blood flow increases resulting in a hard erection.

3. Subsequently, PDE5 enzyme in the penis degrades the cGMP.  As a result the penis returns to the flaccid state.

Erectile Dysfunction

A number of factors contribute to ED.  Vascular issues account for the majority of ED.   As we age, the production of NO decreases. In addition, with time, diet and other health issues such as diabetes, the blood vessels in the penis get clogged.  Consequently, when aroused the blood vessels can not dilate as fully resulting in softer, shorter lasting erections.

Erectile Treatment Options:

  1. PDE5 inhibitors such as Viagra and Cialis are only temporary. The pills, besides causing lots of side effects, eventually stop working as the underlying blockage of the small penile blood vessels worsen.
  2. ICI Trimix shots combine Alprostadil, Phentolamine and Papaverine which result in erections without the side effects of oral medication.
  3. Botox, the newest tool to treat erectile dysfunction, helps relax smooth muscles in the penis.  As a result, the penis is larger and fuller in the relaxed state.  In addition, studies show that Botox improves ED in about 60% of men
  4. RejuvaWAVE® Multiwave Acoustic Wave Therapy or EPAT and Cold Laser.  EPAT, low intensity acoustic wave therapy, similar to lithotripsy that breaks up gall stones and kidney stones, pulverizes the plaque in the microvasculature of the penis. In addition, EPAT stimulates the regeneration and growth of new blood vessels, nerves and muscles.     Unlike Viagra or Trimix, RejuvaWAVE® EPAT turns back the clock and can cure ED restoring spontaneity.
  5. PRP Priapus shot and biologics.   Platelet Rich Plasma using your own body’s platelets and growth factors enhances the effectiveness of EPAT.  In particular, PRP activates your own body’s stem cells to regenerate

Last reviewed and updated 5/28/24 by Simply Men’s Health

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